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BDBM50290352 Acetic acid 1-(4-fluoro-phenyl)-7-naphthalen-1-ylmethyl-4,5,6,7-tetrahydro-1H-indazol-3-ylmethyl ester::CHEMBL85269

SMILES: CC(=O)OCc1nn(c2C(Cc3cccc4ccccc34)CCCc12)-c1ccc(F)cc1

InChI Key: InChIKey=DUCNJELHRZZKGR-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50290352   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Progesterone receptor


(Oryctolagus cuniculus)
BDBM50290352
PNG
(Acetic acid 1-(4-fluoro-phenyl)-7-naphthalen-1-ylm...)
Show SMILES CC(=O)OCc1nn(c2C(Cc3cccc4ccccc34)CCCc12)-c1ccc(F)cc1
Show InChI InChI=1S/C27H25FN2O2/c1-18(31)32-17-26-25-11-5-9-21(16-20-8-4-7-19-6-2-3-10-24(19)20)27(25)30(29-26)23-14-12-22(28)13-15-23/h2-4,6-8,10,12-15,21H,5,9,11,16-17H2,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
n/an/a 73n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity determined by ability to displace [3H]-R5020 radioligand using uterine progesterone receptor obtained from estrogen-primed rabbit


Bioorg Med Chem Lett 7: 2551-2556 (1997)


Article DOI: 10.1016/S0960-894X(97)10016-6
BindingDB Entry DOI: 10.7270/Q2MW2H5C
More data for this
Ligand-Target Pair