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BDBM50290357 7-Biphenyl-4-ylmethyl-1-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-1H-indazole-3-carbaldehyde::CHEMBL83347

SMILES: Fc1ccc(cc1)-n1nc(C=O)c2CCCC(Cc3ccc(cc3)-c3ccccc3)c12

InChI Key: InChIKey=JPXBJBNHLNNRMA-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50290357   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Progesterone receptor


(Oryctolagus cuniculus)
BDBM50290357
PNG
(7-Biphenyl-4-ylmethyl-1-(4-fluoro-phenyl)-4,5,6,7-...)
Show SMILES Fc1ccc(cc1)-n1nc(C=O)c2CCCC(Cc3ccc(cc3)-c3ccccc3)c12
Show InChI InChI=1S/C27H23FN2O/c28-23-13-15-24(16-14-23)30-27-22(7-4-8-25(27)26(18-31)29-30)17-19-9-11-21(12-10-19)20-5-2-1-3-6-20/h1-3,5-6,9-16,18,22H,4,7-8,17H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
n/an/a 1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity determined by ability to displace [3H]-R5020 radioligand using uterine progesterone receptor obtained from estrogen-primed rabbit


Bioorg Med Chem Lett 7: 2551-2556 (1997)


Article DOI: 10.1016/S0960-894X(97)10016-6
BindingDB Entry DOI: 10.7270/Q2MW2H5C
More data for this
Ligand-Target Pair