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BDBM50290363 3-[1,3]Dioxolan-2-yl-1-(4-fluoro-phenyl)-7-naphthalen-1-ylmethyl-4,5,6,7-tetrahydro-1H-indazole::CHEMBL314477

SMILES: Fc1ccc(cc1)-n1nc(C2OCCO2)c2CCCC(Cc3cccc4ccccc34)c12

InChI Key: InChIKey=PYOSGOFNTIDPGD-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50290363   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Progesterone receptor


(Oryctolagus cuniculus)
BDBM50290363
PNG
(3-[1,3]Dioxolan-2-yl-1-(4-fluoro-phenyl)-7-naphtha...)
Show SMILES Fc1ccc(cc1)-n1nc(C2OCCO2)c2CCCC(Cc3cccc4ccccc34)c12
Show InChI InChI=1S/C27H25FN2O2/c28-21-11-13-22(14-12-21)30-26-20(17-19-7-3-6-18-5-1-2-9-23(18)19)8-4-10-24(26)25(29-30)27-31-15-16-32-27/h1-3,5-7,9,11-14,20,27H,4,8,10,15-17H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
n/an/a 97n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity determined by ability to displace [3H]-R5020 radioligand using uterine progesterone receptor obtained from estrogen-primed rabbit


Bioorg Med Chem Lett 7: 2551-2556 (1997)


Article DOI: 10.1016/S0960-894X(97)10016-6
BindingDB Entry DOI: 10.7270/Q2MW2H5C
More data for this
Ligand-Target Pair