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BDBM50290366 7-(3,4-Dimethoxy-benzyl)-1-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-1H-indazole-3-carbaldehyde::CHEMBL85438

SMILES: COc1ccc(CC2CCCc3c(C=O)nn(c23)-c2ccc(F)cc2)cc1OC

InChI Key: InChIKey=AZAXVSUNYNVKLK-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50290366   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Progesterone receptor


(Oryctolagus cuniculus)
BDBM50290366
PNG
(7-(3,4-Dimethoxy-benzyl)-1-(4-fluoro-phenyl)-4,5,6...)
Show SMILES COc1ccc(CC2CCCc3c(C=O)nn(c23)-c2ccc(F)cc2)cc1OC
Show InChI InChI=1S/C23H23FN2O3/c1-28-21-11-6-15(13-22(21)29-2)12-16-4-3-5-19-20(14-27)25-26(23(16)19)18-9-7-17(24)8-10-18/h6-11,13-14,16H,3-5,12H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
n/an/a 1.89E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity determined by ability to displace [3H]-R5020 radioligand using uterine progesterone receptor obtained from estrogen-primed rabbit


Bioorg Med Chem Lett 7: 2551-2556 (1997)


Article DOI: 10.1016/S0960-894X(97)10016-6
BindingDB Entry DOI: 10.7270/Q2MW2H5C
More data for this
Ligand-Target Pair