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BDBM50290372 1-(4-Fluoro-phenyl)-7-naphthalen-2-ylmethyl-octahydro-indazole-3-carbaldehyde::CHEMBL86134

SMILES: Fc1ccc(cc1)N1NC(C=O)C2CCCC(Cc3ccc4ccccc4c3)C12

InChI Key: InChIKey=IMIIJCMZDCPQOD-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50290372   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Progesterone receptor


(Oryctolagus cuniculus)
BDBM50290372
PNG
(1-(4-Fluoro-phenyl)-7-naphthalen-2-ylmethyl-octahy...)
Show SMILES Fc1ccc(cc1)N1NC(C=O)C2CCCC(Cc3ccc4ccccc4c3)C12
Show InChI InChI=1S/C25H25FN2O/c26-21-10-12-22(13-11-21)28-25-20(6-3-7-23(25)24(16-29)27-28)15-17-8-9-18-4-1-2-5-19(18)14-17/h1-2,4-5,8-14,16,20,23-25,27H,3,6-7,15H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
n/an/a 56n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity determined by ability to displace [3H]-R5020 radioligand using uterine progesterone receptor obtained from estrogen-primed rabbit


Bioorg Med Chem Lett 7: 2551-2556 (1997)


Article DOI: 10.1016/S0960-894X(97)10016-6
BindingDB Entry DOI: 10.7270/Q2MW2H5C
More data for this
Ligand-Target Pair