BDBM50290629 (S)-2-Pyrrolidin-2-yl-furo[3,2-b]pyridine::CHEMBL91005

SMILES: C1CN[C@@H](C1)c1cc2ncccc2o1

InChI Key: InChIKey=QULUBEZVAACGFX-QMMMGPOBSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50290629   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
alpha-1 Nicotinic AChR (Homo sapiens (Human))	BDBM50290629 ((S)-2-Pyrrolidin-2-yl-furo[3,2-b]pyridine | CHEMBL...) Show SMILES C1CN[C@@H](C1)c1cc2ncccc2o1 Show InChI InChI=1S/C11H12N2O/c1-3-8(12-5-1)11-7-9-10(14-11)4-2-6-13-9/h2,4,6-8,12H,1,3,5H2/t8-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for functional activity against neuronal nicotinic acetylcholine receptor(nAChR) expressed in K177 cells using isotopic rubidium efflux assay.				Bioorg Med Chem Lett 7: 2703-2708 (1997) Article DOI: 10.1016/S0960-894X(97)10080-4 BindingDB Entry DOI: 10.7270/Q2Z60P30
					More data for this Ligand-Target Pair