Found 4 hits for monomerid = 50290633 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Macrophage colony stimulating factor receptor
(Homo sapiens (Human)) | BDBM50290633
(4-(2,3-Dihydro-indol-1-yl)-6,7-dimethoxy-quinazoli...)Show InChI InChI=1S/C18H17N3O2/c1-22-16-9-13-14(10-17(16)23-2)19-11-20-18(13)21-8-7-12-5-3-4-6-15(12)21/h3-6,9-11H,7-8H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Antagonism towards Colony stimulating factor 1 receptor (CSF-1R) |
Bioorg Med Chem Lett 7: 421-424 (1997)
Article DOI: 10.1016/S0960-894X(97)00035-8 BindingDB Entry DOI: 10.7270/Q2SB45RN |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50290633
(4-(2,3-Dihydro-indol-1-yl)-6,7-dimethoxy-quinazoli...)Show InChI InChI=1S/C18H17N3O2/c1-22-16-9-13-14(10-17(16)23-2)19-11-20-18(13)21-8-7-12-5-3-4-6-15(12)21/h3-6,9-11H,7-8H2,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of EGF-stimulated proliferation of KB cells in culture |
Bioorg Med Chem Lett 7: 2723-2728 (1997)
Article DOI: 10.1016/S0960-894X(97)10059-2 BindingDB Entry DOI: 10.7270/Q2TD9XCQ |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50290633
(4-(2,3-Dihydro-indol-1-yl)-6,7-dimethoxy-quinazoli...)Show InChI InChI=1S/C18H17N3O2/c1-22-16-9-13-14(10-17(16)23-2)19-11-20-18(13)21-8-7-12-5-3-4-6-15(12)21/h3-6,9-11H,7-8H2,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 820 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Tested for inhibition of Epidermal growth factor receptor from A431 vulval squamous carcinoma cells |
Bioorg Med Chem Lett 7: 2723-2728 (1997)
Article DOI: 10.1016/S0960-894X(97)10059-2 BindingDB Entry DOI: 10.7270/Q2TD9XCQ |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50290633
(4-(2,3-Dihydro-indol-1-yl)-6,7-dimethoxy-quinazoli...)Show InChI InChI=1S/C18H17N3O2/c1-22-16-9-13-14(10-17(16)23-2)19-11-20-18(13)21-8-7-12-5-3-4-6-15(12)21/h3-6,9-11H,7-8H2,1-2H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Antagonism towards Epidermal growth factor receptor |
Bioorg Med Chem Lett 7: 421-424 (1997)
Article DOI: 10.1016/S0960-894X(97)00035-8 BindingDB Entry DOI: 10.7270/Q2SB45RN |
More data for this Ligand-Target Pair | |