BDBM50290660 (2E,4E)-3-Methyl-5-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-cyclopropyl]-penta-2,4-dienoic acid::CHEMBL92284

SMILES: C\C(\C=C\C1(CC1)c1cc2c(cc1C)C(C)(C)CCC2(C)C)=C/C(O)=O

InChI Key: InChIKey=QCUYSUZEBJQJPS-YWRSBGDESA-N

Data: 6 KI  4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50290660   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50290660 ((2E,4E)-3-Methyl-5-[1-(3,5,5,8,8-pentamethyl-5,6,7...) Show SMILES C\C(\C=C\C1(CC1)c1cc2c(cc1C)C(C)(C)CCC2(C)C)=C/C(O)=O Show InChI InChI=1S/C24H32O2/c1-16(13-21(25)26)7-8-24(11-12-24)18-15-20-19(14-17(18)2)22(3,4)9-10-23(20,5)6/h7-8,13-15H,9-12H2,1-6H3,(H,25,26)/b8-7+,16-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]-9-cis-RA binding to RXR alpha receptor				Bioorg Med Chem Lett 7: 2747-2752 (1997) Article DOI: 10.1016/S0960-894X(97)10079-8 BindingDB Entry DOI: 10.7270/Q2JW8DW6
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50290660 ((2E,4E)-3-Methyl-5-[1-(3,5,5,8,8-pentamethyl-5,6,7...) Show SMILES C\C(\C=C\C1(CC1)c1cc2c(cc1C)C(C)(C)CCC2(C)C)=C/C(O)=O Show InChI InChI=1S/C24H32O2/c1-16(13-21(25)26)7-8-24(11-12-24)18-15-20-19(14-17(18)2)22(3,4)9-10-23(20,5)6/h7-8,13-15H,9-12H2,1-6H3,(H,25,26)/b8-7+,16-13+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]-9-cis-RA binding to RXR beta receptor				Bioorg Med Chem Lett 7: 2747-2752 (1997) Article DOI: 10.1016/S0960-894X(97)10079-8 BindingDB Entry DOI: 10.7270/Q2JW8DW6
					More data for this Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha (Homo sapiens (Human))	BDBM50290660 ((2E,4E)-3-Methyl-5-[1-(3,5,5,8,8-pentamethyl-5,6,7...) Show SMILES C\C(\C=C\C1(CC1)c1cc2c(cc1C)C(C)(C)CCC2(C)C)=C/C(O)=O Show InChI InChI=1S/C24H32O2/c1-16(13-21(25)26)7-8-24(11-12-24)18-15-20-19(14-17(18)2)22(3,4)9-10-23(20,5)6/h7-8,13-15H,9-12H2,1-6H3,(H,25,26)/b8-7+,16-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Transcriptional activation in CV-1 cells expressing retinoid X receptor RXR gamma				Bioorg Med Chem Lett 7: 2747-2752 (1997) Article DOI: 10.1016/S0960-894X(97)10079-8 BindingDB Entry DOI: 10.7270/Q2JW8DW6
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50290660 ((2E,4E)-3-Methyl-5-[1-(3,5,5,8,8-pentamethyl-5,6,7...) Show SMILES C\C(\C=C\C1(CC1)c1cc2c(cc1C)C(C)(C)CCC2(C)C)=C/C(O)=O Show InChI InChI=1S/C24H32O2/c1-16(13-21(25)26)7-8-24(11-12-24)18-15-20-19(14-17(18)2)22(3,4)9-10-23(20,5)6/h7-8,13-15H,9-12H2,1-6H3,(H,25,26)/b8-7+,16-13+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]-ATRA binding to RAR beta receptor				Bioorg Med Chem Lett 7: 2747-2752 (1997) Article DOI: 10.1016/S0960-894X(97)10079-8 BindingDB Entry DOI: 10.7270/Q2JW8DW6
					More data for this Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha (Homo sapiens (Human))	BDBM50290660 ((2E,4E)-3-Methyl-5-[1-(3,5,5,8,8-pentamethyl-5,6,7...) Show SMILES C\C(\C=C\C1(CC1)c1cc2c(cc1C)C(C)(C)CCC2(C)C)=C/C(O)=O Show InChI InChI=1S/C24H32O2/c1-16(13-21(25)26)7-8-24(11-12-24)18-15-20-19(14-17(18)2)22(3,4)9-10-23(20,5)6/h7-8,13-15H,9-12H2,1-6H3,(H,25,26)/b8-7+,16-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]-ATRA binding to RAR alpha receptor				Bioorg Med Chem Lett 7: 2747-2752 (1997) Article DOI: 10.1016/S0960-894X(97)10079-8 BindingDB Entry DOI: 10.7270/Q2JW8DW6
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50290660 ((2E,4E)-3-Methyl-5-[1-(3,5,5,8,8-pentamethyl-5,6,7...) Show SMILES C\C(\C=C\C1(CC1)c1cc2c(cc1C)C(C)(C)CCC2(C)C)=C/C(O)=O Show InChI InChI=1S/C24H32O2/c1-16(13-21(25)26)7-8-24(11-12-24)18-15-20-19(14-17(18)2)22(3,4)9-10-23(20,5)6/h7-8,13-15H,9-12H2,1-6H3,(H,25,26)/b8-7+,16-13+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]-ATRA bindng to RAR gamma receptor				Bioorg Med Chem Lett 7: 2747-2752 (1997) Article DOI: 10.1016/S0960-894X(97)10079-8 BindingDB Entry DOI: 10.7270/Q2JW8DW6
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50290660 ((2E,4E)-3-Methyl-5-[1-(3,5,5,8,8-pentamethyl-5,6,7...) Show SMILES C\C(\C=C\C1(CC1)c1cc2c(cc1C)C(C)(C)CCC2(C)C)=C/C(O)=O Show InChI InChI=1S/C24H32O2/c1-16(13-21(25)26)7-8-24(11-12-24)18-15-20-19(14-17(18)2)22(3,4)9-10-23(20,5)6/h7-8,13-15H,9-12H2,1-6H3,(H,25,26)/b8-7+,16-13+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Transcriptional activation in CV-1 cells expressing retinoid X receptor RXR beta				Bioorg Med Chem Lett 7: 2747-2752 (1997) Article DOI: 10.1016/S0960-894X(97)10079-8 BindingDB Entry DOI: 10.7270/Q2JW8DW6
					More data for this Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha (Homo sapiens (Human))	BDBM50290660 ((2E,4E)-3-Methyl-5-[1-(3,5,5,8,8-pentamethyl-5,6,7...) Show SMILES C\C(\C=C\C1(CC1)c1cc2c(cc1C)C(C)(C)CCC2(C)C)=C/C(O)=O Show InChI InChI=1S/C24H32O2/c1-16(13-21(25)26)7-8-24(11-12-24)18-15-20-19(14-17(18)2)22(3,4)9-10-23(20,5)6/h7-8,13-15H,9-12H2,1-6H3,(H,25,26)/b8-7+,16-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Transcriptional activation in CV-1 cells expressing retinoid X receptor RXR gamma				Bioorg Med Chem Lett 7: 2747-2752 (1997) Article DOI: 10.1016/S0960-894X(97)10079-8 BindingDB Entry DOI: 10.7270/Q2JW8DW6
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha/gamma (Homo sapiens (Human))	BDBM50290660 ((2E,4E)-3-Methyl-5-[1-(3,5,5,8,8-pentamethyl-5,6,7...) Show SMILES C\C(\C=C\C1(CC1)c1cc2c(cc1C)C(C)(C)CCC2(C)C)=C/C(O)=O Show InChI InChI=1S/C24H32O2/c1-16(13-21(25)26)7-8-24(11-12-24)18-15-20-19(14-17(18)2)22(3,4)9-10-23(20,5)6/h7-8,13-15H,9-12H2,1-6H3,(H,25,26)/b8-7+,16-13+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	144	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Transcriptional activation in CV-1 cells expressing retinoid X receptor RXR gamma				Bioorg Med Chem Lett 7: 2747-2752 (1997) Article DOI: 10.1016/S0960-894X(97)10079-8 BindingDB Entry DOI: 10.7270/Q2JW8DW6
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50290660 ((2E,4E)-3-Methyl-5-[1-(3,5,5,8,8-pentamethyl-5,6,7...) Show SMILES C\C(\C=C\C1(CC1)c1cc2c(cc1C)C(C)(C)CCC2(C)C)=C/C(O)=O Show InChI InChI=1S/C24H32O2/c1-16(13-21(25)26)7-8-24(11-12-24)18-15-20-19(14-17(18)2)22(3,4)9-10-23(20,5)6/h7-8,13-15H,9-12H2,1-6H3,(H,25,26)/b8-7+,16-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Transcriptional activation in CV-1 cells expressing retinoid X receptor RXR alpha				Bioorg Med Chem Lett 7: 2747-2752 (1997) Article DOI: 10.1016/S0960-894X(97)10079-8 BindingDB Entry DOI: 10.7270/Q2JW8DW6
					More data for this Ligand-Target Pair