BDBM50290849 (3,4-Dimethoxy-phenyl)-(6,7-dimethoxy-quinolin-4-yl)-amine::CHEMBL98137
SMILES: COc1ccc(Nc2ccnc3cc(OC)c(OC)cc23)cc1OC
InChI Key: InChIKey=PPOIGSDSVMYNSD-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50290849 ((3,4-Dimethoxy-phenyl)-(6,7-dimethoxy-quinolin-4-y...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 8.05E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of epidermal growth factor receptor (EGF-R) autophosphorylation in A431 cells | Bioorg Med Chem Lett 7: 2935-2940 (1997) Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor (PDGFr) (Rattus norvegicus) | BDBM50290849 ((3,4-Dimethoxy-phenyl)-(6,7-dimethoxy-quinolin-4-y...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells. | Bioorg Med Chem Lett 7: 2935-2940 (1997) Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R | |||||||||||
More data for this Ligand-Target Pair |