BDBM50291024 (2R,3R,4R,5S)-2-Hydroxymethyl-1-(2-trimethylsilanyl-benzyl)-piperidine-3,4,5-triol::CHEMBL323803

SMILES: C[Si](C)(C)c1ccccc1CN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO

InChI Key: InChIKey=VGIFLHFJUSALIL-OCVGTWLNSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50291024   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sucrase-isomaltase (Rattus norvegicus (Rat))	BDBM50291024 ((2R,3R,4R,5S)-2-Hydroxymethyl-1-(2-trimethylsilany...) Show SMILES C[Si](C)(C)c1ccccc1CN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO Show InChI InChI=1S/C16H27NO4Si/c1-22(2,3)14-7-5-4-6-11(14)8-17-9-13(19)16(21)15(20)12(17)10-18/h4-7,12-13,15-16,18-21H,8-10H2,1-3H3/t12-,13+,15-,16-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for the inhibition constant against rat small intestinal sucrase				Bioorg Med Chem Lett 7: 355-360 (1997) Article DOI: 10.1016/S0960-894X(97)00012-7 BindingDB Entry DOI: 10.7270/Q2F18ZQ1
					More data for this Ligand-Target Pair
alpha-Glucosidase (α-Glucosidase) (Rattus norvegicus (Rat))	BDBM50291024 ((2R,3R,4R,5S)-2-Hydroxymethyl-1-(2-trimethylsilany...) Show SMILES C[Si](C)(C)c1ccccc1CN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO Show InChI InChI=1S/C16H27NO4Si/c1-22(2,3)14-7-5-4-6-11(14)8-17-9-13(19)16(21)15(20)12(17)10-18/h4-7,12-13,15-16,18-21H,8-10H2,1-3H3/t12-,13+,15-,16-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for the inhibition constant against rat small intestinal sucrase				Bioorg Med Chem Lett 7: 355-360 (1997) Article DOI: 10.1016/S0960-894X(97)00012-7 BindingDB Entry DOI: 10.7270/Q2F18ZQ1
					More data for this Ligand-Target Pair
Maltase-glucoamylase (Homo sapiens (Human))	BDBM50291024 ((2R,3R,4R,5S)-2-Hydroxymethyl-1-(2-trimethylsilany...) Show SMILES C[Si](C)(C)c1ccccc1CN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO Show InChI InChI=1S/C16H27NO4Si/c1-22(2,3)14-7-5-4-6-11(14)8-17-9-13(19)16(21)15(20)12(17)10-18/h4-7,12-13,15-16,18-21H,8-10H2,1-3H3/t12-,13+,15-,16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition constant against rat small intestinal glucoamylase				Bioorg Med Chem Lett 7: 355-360 (1997) Article DOI: 10.1016/S0960-894X(97)00012-7 BindingDB Entry DOI: 10.7270/Q2F18ZQ1
					More data for this Ligand-Target Pair