BDBM50291033 (2R,3R,4R,5S)-1-[(Dimethyl-phenyl-silanyl)-methyl]-2-hydroxymethyl-piperidine-3,4,5-triol::CHEMBL333917

SMILES: C[Si](C)(CN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO)c1ccccc1

InChI Key: InChIKey=VIBQKRMTVGOHPD-LXTVHRRPSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50291033   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
alpha-Glucosidase (α-Glucosidase) (Rattus norvegicus (Rat))	BDBM50291033 ((2R,3R,4R,5S)-1-[(Dimethyl-phenyl-silanyl)-methyl]...) Show SMILES C[Si](C)(CN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO)c1ccccc1 Show InChI InChI=1S/C15H25NO4Si/c1-21(2,11-6-4-3-5-7-11)10-16-8-13(18)15(20)14(19)12(16)9-17/h3-7,12-15,17-20H,8-10H2,1-2H3/t12-,13+,14-,15-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for the inhibition constant against rat small intestinal sucrase				Bioorg Med Chem Lett 7: 355-360 (1997) Article DOI: 10.1016/S0960-894X(97)00012-7 BindingDB Entry DOI: 10.7270/Q2F18ZQ1
					More data for this Ligand-Target Pair
Maltase-glucoamylase (Homo sapiens (Human))	BDBM50291033 ((2R,3R,4R,5S)-1-[(Dimethyl-phenyl-silanyl)-methyl]...) Show SMILES C[Si](C)(CN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO)c1ccccc1 Show InChI InChI=1S/C15H25NO4Si/c1-21(2,11-6-4-3-5-7-11)10-16-8-13(18)15(20)14(19)12(16)9-17/h3-7,12-15,17-20H,8-10H2,1-2H3/t12-,13+,14-,15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition constant against rat small intestinal glucoamylase				Bioorg Med Chem Lett 7: 355-360 (1997) Article DOI: 10.1016/S0960-894X(97)00012-7 BindingDB Entry DOI: 10.7270/Q2F18ZQ1
					More data for this Ligand-Target Pair
Sucrase-isomaltase (Rattus norvegicus (Rat))	BDBM50291033 ((2R,3R,4R,5S)-1-[(Dimethyl-phenyl-silanyl)-methyl]...) Show SMILES C[Si](C)(CN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO)c1ccccc1 Show InChI InChI=1S/C15H25NO4Si/c1-21(2,11-6-4-3-5-7-11)10-16-8-13(18)15(20)14(19)12(16)9-17/h3-7,12-15,17-20H,8-10H2,1-2H3/t12-,13+,14-,15-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for the inhibition constant against rat small intestinal sucrase				Bioorg Med Chem Lett 7: 355-360 (1997) Article DOI: 10.1016/S0960-894X(97)00012-7 BindingDB Entry DOI: 10.7270/Q2F18ZQ1
					More data for this Ligand-Target Pair