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BDBM50291109 (6,7-Dimethyl-quinazolin-4-yl)-methyl-m-tolyl-amine; hydrochloride::CHEMBL554566

SMILES: CN(c1cccc(C)c1)c1ncnc2cc(C)c(C)cc12

InChI Key: InChIKey=APLZPLMCUGKELH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50291109   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Macrophage colony stimulating factor receptor


(Homo sapiens (Human))
BDBM50291109
PNG
((6,7-Dimethyl-quinazolin-4-yl)-methyl-m-tolyl-amin...)
Show SMILES CN(c1cccc(C)c1)c1ncnc2cc(C)c(C)cc12
Show InChI InChI=1S/C18H19N3/c1-12-6-5-7-15(8-12)21(4)18-16-9-13(2)14(3)10-17(16)19-11-20-18/h5-11H,1-4H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 1.60E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Antagonism towards Colony stimulating factor 1 receptor (CSF-1R)


Bioorg Med Chem Lett 7: 421-424 (1997)


Article DOI: 10.1016/S0960-894X(97)00035-8
BindingDB Entry DOI: 10.7270/Q2SB45RN
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50291109
PNG
((6,7-Dimethyl-quinazolin-4-yl)-methyl-m-tolyl-amin...)
Show SMILES CN(c1cccc(C)c1)c1ncnc2cc(C)c(C)cc12
Show InChI InChI=1S/C18H19N3/c1-12-6-5-7-15(8-12)21(4)18-16-9-13(2)14(3)10-17(16)19-11-20-18/h5-11H,1-4H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 6.50E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Antagonism towards Epidermal growth factor receptor


Bioorg Med Chem Lett 7: 421-424 (1997)


Article DOI: 10.1016/S0960-894X(97)00035-8
BindingDB Entry DOI: 10.7270/Q2SB45RN
More data for this
Ligand-Target Pair