BDBM50291111 (6,7-Dimethoxy-quinazolin-4-yl)-methyl-m-tolyl-amine; hydrochloride::CHEMBL553523
SMILES: COc1cc2ncnc(N(C)c3cccc(C)c3)c2cc1OC
InChI Key: InChIKey=VEFMMRYJRFCGMZ-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Macrophage colony stimulating factor receptor (Homo sapiens (Human)) | BDBM50291111 ((6,7-Dimethoxy-quinazolin-4-yl)-methyl-m-tolyl-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonism towards Colony stimulating factor 1 receptor (CSF-1R) | Bioorg Med Chem Lett 7: 421-424 (1997) Article DOI: 10.1016/S0960-894X(97)00035-8 BindingDB Entry DOI: 10.7270/Q2SB45RN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50291111 ((6,7-Dimethoxy-quinazolin-4-yl)-methyl-m-tolyl-ami...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonism towards Epidermal growth factor receptor | Bioorg Med Chem Lett 7: 421-424 (1997) Article DOI: 10.1016/S0960-894X(97)00035-8 BindingDB Entry DOI: 10.7270/Q2SB45RN | |||||||||||
More data for this Ligand-Target Pair |