BDBM50291114 (4-Chloro-phenyl)-(6,7-dimethoxy-quinazolin-4-yl)-methyl-amine; hydrochloride::CHEMBL543195

SMILES: COc1cc2ncnc(N(C)c3ccc(Cl)cc3)c2cc1OC

InChI Key: InChIKey=PKOUZZXESDCMFW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50291114   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50291114 ((4-Chloro-phenyl)-(6,7-dimethoxy-quinazolin-4-yl)-...) Show SMILES COc1cc2ncnc(N(C)c3ccc(Cl)cc3)c2cc1OC Show InChI InChI=1S/C17H16ClN3O2/c1-21(12-6-4-11(18)5-7-12)17-13-8-15(22-2)16(23-3)9-14(13)19-10-20-17/h4-10H,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonism towards Epidermal growth factor receptor				Bioorg Med Chem Lett 7: 421-424 (1997) Article DOI: 10.1016/S0960-894X(97)00035-8 BindingDB Entry DOI: 10.7270/Q2SB45RN
					More data for this Ligand-Target Pair
Macrophage colony stimulating factor receptor (Homo sapiens (Human))	BDBM50291114 ((4-Chloro-phenyl)-(6,7-dimethoxy-quinazolin-4-yl)-...) Show SMILES COc1cc2ncnc(N(C)c3ccc(Cl)cc3)c2cc1OC Show InChI InChI=1S/C17H16ClN3O2/c1-21(12-6-4-11(18)5-7-12)17-13-8-15(22-2)16(23-3)9-14(13)19-10-20-17/h4-10H,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonism towards Colony stimulating factor 1 receptor (CSF-1R)				Bioorg Med Chem Lett 7: 421-424 (1997) Article DOI: 10.1016/S0960-894X(97)00035-8 BindingDB Entry DOI: 10.7270/Q2SB45RN
					More data for this Ligand-Target Pair