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BDBM50291117 CHEMBL135928::Methyl-phenyl-(2,6,7-trimethoxy-quinazolin-4-yl)-amine

SMILES: COc1cc2nc(OC)nc(N(C)c3ccccc3)c2cc1OC

InChI Key: InChIKey=HGYDHIOYJUARCE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50291117   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50291117
PNG
(CHEMBL135928 | Methyl-phenyl-(2,6,7-trimethoxy-qui...)
Show SMILES COc1cc2nc(OC)nc(N(C)c3ccccc3)c2cc1OC
Show InChI InChI=1S/C18H19N3O3/c1-21(12-8-6-5-7-9-12)17-13-10-15(22-2)16(23-3)11-14(13)19-18(20-17)24-4/h5-11H,1-4H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
n/an/a>5.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Antagonism towards Epidermal growth factor receptor


Bioorg Med Chem Lett 7: 421-424 (1997)


Article DOI: 10.1016/S0960-894X(97)00035-8
BindingDB Entry DOI: 10.7270/Q2SB45RN
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM50291117
PNG
(CHEMBL135928 | Methyl-phenyl-(2,6,7-trimethoxy-qui...)
Show SMILES COc1cc2nc(OC)nc(N(C)c3ccccc3)c2cc1OC
Show InChI InChI=1S/C18H19N3O3/c1-21(12-8-6-5-7-9-12)17-13-10-15(22-2)16(23-3)11-14(13)19-18(20-17)24-4/h5-11H,1-4H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
n/an/a>5.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Antagonism towards Colony stimulating factor 1 receptor (CSF-1R)


Bioorg Med Chem Lett 7: 421-424 (1997)


Article DOI: 10.1016/S0960-894X(97)00035-8
BindingDB Entry DOI: 10.7270/Q2SB45RN
More data for this
Ligand-Target Pair