BDBM50291388 3-[(E)-4-(4-Adamantan-1-yl-3-hydroxy-phenyl)-1-((E)-2-carboxy-1-methyl-vinyl)-but-1-enyl]-benzoic acid::CHEMBL444079
SMILES: C\C(=C/C(O)=O)\C(=C\CCc1ccc(c(O)c1)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2)\c1cccc(c1)C(O)=O
InChI Key: InChIKey=BUERRQGWQZXDOG-JBVROQKXSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cPLA2 C2 (Homo sapiens (Human)) | BDBM50291388 (3-[(E)-4-(4-Adamantan-1-yl-3-hydroxy-phenyl)-1-((E...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was measured for the inhibition of human platelet PLA2 (HP-PLA2) | Bioorg Med Chem Lett 7: 793-798 (1997) Article DOI: 10.1016/S0960-894X(97)00110-8 BindingDB Entry DOI: 10.7270/Q26D5T0F | |||||||||||
More data for this Ligand-Target Pair |