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BDBM50291389 3-{(E)-3-Carbamoyl-2-methyl-1-[1-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-anthracen-2-yl)-meth-(E)-ylidene]-allyl}-benzamide::CHEMBL424386

SMILES: C\C(=C/C(N)=O)\C(=C\c1ccc2cc3c(cc2c1)C(C)(C)CCC3(C)C)\c1cccc(c1)C(N)=O

InChI Key: InChIKey=MWLTYZJQCIBUFG-KGOGZVLYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50291389   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cPLA2 C2


(Homo sapiens (Human))		BDBM50291389
PNG
(3-{(E)-3-Carbamoyl-2-methyl-1-[1-(5,5,8,8-tetramet...)
Show SMILES C\C(=C/C(N)=O)\C(=C\c1ccc2cc3c(cc2c1)C(C)(C)CCC3(C)C)\c1cccc(c1)C(N)=O
Show InChI InChI=1S/C31H34N2O2/c1-19(13-28(32)34)25(22-7-6-8-23(16-22)29(33)35)15-20-9-10-21-17-26-27(18-24(21)14-20)31(4,5)12-11-30(26,2)3/h6-10,13-18H,11-12H2,1-5H3,(H2,32,34)(H2,33,35)/b19-13+,25-15-
PDB
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KEGG

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PC cid
PC sid
UniChem
Article
n/an/a 4.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was measured for the inhibition of human platelet PLA2 (HP-PLA2)

Bioorg Med Chem Lett 7: 793-798 (1997)


Article DOI: 10.1016/S0960-894X(97)00110-8
BindingDB Entry DOI: 10.7270/Q26D5T0F
More data for this
Ligand-Target Pair