BDBM50291396 5-{2-[4-(4-Ethylamino-butyl)-piperidin-1-yl]-acetyl}-5,10-dihydro-dibenzo[b,e][1,4]diazepin-11-one::CHEMBL355874
SMILES: CCNCCCCC1CCN(CC(=O)N2c3ccccc3NC(=O)c3ccccc23)CC1
InChI Key: InChIKey=CKABNURNABKRSF-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human)) | BDBM50291396 (5-{2-[4-(4-Ethylamino-butyl)-piperidin-1-yl]-acety...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested in vitro for the binding affinity against muscarinic receptor subtype 2 (M2) | Bioorg Med Chem Lett 7: 799-804 (1997) Article DOI: 10.1016/S0960-894X(97)00109-1 BindingDB Entry DOI: 10.7270/Q22N529J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human)) | BDBM50291396 (5-{2-[4-(4-Ethylamino-butyl)-piperidin-1-yl]-acety...) | UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested in vitro for the binding affinity against muscarinic receptor subtype 1 (M1) | Bioorg Med Chem Lett 7: 799-804 (1997) Article DOI: 10.1016/S0960-894X(97)00109-1 BindingDB Entry DOI: 10.7270/Q22N529J | |||||||||||
More data for this Ligand-Target Pair |