null

SMILES: C(OC1=NOCC1)C#CCN1CCCC1

InChI Key: InChIKey=JBWNQBYECBRHET-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50291550   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50291550 (3-(4-Pyrrolidin-1-yl-but-2-ynyloxy)-4,5-dihydro-is...) Show SMILES C(OC1=NOCC1)C#CCN1CCCC1 |t:2| Show InChI InChI=1S/C11H16N2O2/c1-2-7-13(6-1)8-3-4-9-14-11-5-10-15-12-11/h1-2,5-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	233	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Muscarinic receptor M2 in rat heart using [3H]-QNB (quinuclidinyl benzylate) radioligand as a M2 non-selective muscarinic receptor antagonist at a co...				Bioorg Med Chem Lett 7: 1033-1036 (1997) Article DOI: 10.1016/S0960-894X(97)00150-9 BindingDB Entry DOI: 10.7270/Q2S46RZ2
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50291550 (3-(4-Pyrrolidin-1-yl-but-2-ynyloxy)-4,5-dihydro-is...) Show SMILES C(OC1=NOCC1)C#CCN1CCCC1 |t:2| Show InChI InChI=1S/C11H16N2O2/c1-2-7-13(6-1)8-3-4-9-14-11-5-10-15-12-11/h1-2,5-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	8.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against Muscarinic receptor M2 in rat brain using [3H]QNB (quinuclidinyl benzylate) radioligand at a concentration of 0.12 nM				Bioorg Med Chem Lett 7: 1033-1036 (1997) Article DOI: 10.1016/S0960-894X(97)00150-9 BindingDB Entry DOI: 10.7270/Q2S46RZ2
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50291550 (3-(4-Pyrrolidin-1-yl-but-2-ynyloxy)-4,5-dihydro-is...) Show SMILES C(OC1=NOCC1)C#CCN1CCCC1 |t:2| Show InChI InChI=1S/C11H16N2O2/c1-2-7-13(6-1)8-3-4-9-14-11-5-10-15-12-11/h1-2,5-10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was assessed for the binding affinity against muscarinic receptor subtypes in rat brain using [3H]OXO-M radioligand as a muscarinic receptor...				Bioorg Med Chem Lett 7: 1033-1036 (1997) Article DOI: 10.1016/S0960-894X(97)00150-9 BindingDB Entry DOI: 10.7270/Q2S46RZ2
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50291550 (3-(4-Pyrrolidin-1-yl-but-2-ynyloxy)-4,5-dihydro-is...) Show SMILES C(OC1=NOCC1)C#CCN1CCCC1 |t:2| Show InChI InChI=1S/C11H16N2O2/c1-2-7-13(6-1)8-3-4-9-14-11-5-10-15-12-11/h1-2,5-10H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	412	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against Muscarinic receptor M1 in rat brain using [3H]-PZ (pirenzepine) radioligand at a concentration of 1 nM				Bioorg Med Chem Lett 7: 1033-1036 (1997) Article DOI: 10.1016/S0960-894X(97)00150-9 BindingDB Entry DOI: 10.7270/Q2S46RZ2
					More data for this Ligand-Target Pair