BDBM50291561 CHEMBL10251::{1-[(S)-2-Biphenyl-4-yl-1-(1H-tetrazol-5-yl)-ethylamino]-2-naphthalen-1-yl-ethyl}-phosphonic acid

SMILES: OP(O)(=O)C(Cc1cccc2ccccc12)N[C@@H](Cc1ccc(cc1)-c1ccccc1)c1nnn[nH]1

InChI Key: InChIKey=UGLAENRVRPVULB-PMCHYTPCSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50291561   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin-converting enzyme 1 (ECE1) (Homo sapiens (Human))	BDBM50291561 (CHEMBL10251 | {1-[(S)-2-Biphenyl-4-yl-1-(1H-tetraz...) Show SMILES OP(O)(=O)C(Cc1cccc2ccccc12)N[C@@H](Cc1ccc(cc1)-c1ccccc1)c1nnn[nH]1 Show InChI InChI=1S/C27H26N5O3P/c33-36(34,35)26(18-23-11-6-10-22-9-4-5-12-24(22)23)28-25(27-29-31-32-30-27)17-19-13-15-21(16-14-19)20-7-2-1-3-8-20/h1-16,25-26,28H,17-18H2,(H2,33,34,35)(H,29,30,31,32)/t25-,26?/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition against recombinant human Endothelin converting enzyme 1 activity				Bioorg Med Chem Lett 7: 1059-1064 (1997) Article DOI: 10.1016/S0960-894X(97)00159-5 BindingDB Entry DOI: 10.7270/Q2WH2QGK
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM50291561 (CHEMBL10251 | {1-[(S)-2-Biphenyl-4-yl-1-(1H-tetraz...) Show SMILES OP(O)(=O)C(Cc1cccc2ccccc12)N[C@@H](Cc1ccc(cc1)-c1ccccc1)c1nnn[nH]1 Show InChI InChI=1S/C27H26N5O3P/c33-36(34,35)26(18-23-11-6-10-22-9-4-5-12-24(22)23)28-25(27-29-31-32-30-27)17-19-13-15-21(16-14-19)20-7-2-1-3-8-20/h1-16,25-26,28H,17-18H2,(H2,33,34,35)(H,29,30,31,32)/t25-,26?/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of neutral endopeptidase 24.11(NEP)				Bioorg Med Chem Lett 7: 1059-1064 (1997) Article DOI: 10.1016/S0960-894X(97)00159-5 BindingDB Entry DOI: 10.7270/Q2WH2QGK
					More data for this Ligand-Target Pair