BDBM50291601 1-(4-Diisopropylamino-but-2-ynyl)-3,3-diphenyl-pyrrolidine-2,5-dione::CHEMBL368792

SMILES: CC(C)N(CC#CCN1C(=O)CC(C1=O)(c1ccccc1)c1ccccc1)C(C)C

InChI Key: InChIKey=KLGANUHFFONXJC-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50291601   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50291601 (1-(4-Diisopropylamino-but-2-ynyl)-3,3-diphenyl-pyr...) Show SMILES CC(C)N(CC#CCN1C(=O)CC(C1=O)(c1ccccc1)c1ccccc1)C(C)C Show InChI InChI=1S/C26H30N2O2/c1-20(2)27(21(3)4)17-11-12-18-28-24(29)19-26(25(28)30,22-13-7-5-8-14-22)23-15-9-6-10-16-23/h5-10,13-16,20-21H,17-19H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]QNB (quinuclidinyl benzylate) from muscarinic M2 receptor of rat heart homogenates.				Bioorg Med Chem Lett 7: 979-984 (1997) Article DOI: 10.1016/S0960-894X(97)00143-1 BindingDB Entry DOI: 10.7270/Q2N29XFM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50291601 (1-(4-Diisopropylamino-but-2-ynyl)-3,3-diphenyl-pyr...) Show SMILES CC(C)N(CC#CCN1C(=O)CC(C1=O)(c1ccccc1)c1ccccc1)C(C)C Show InChI InChI=1S/C26H30N2O2/c1-20(2)27(21(3)4)17-11-12-18-28-24(29)19-26(25(28)30,22-13-7-5-8-14-22)23-15-9-6-10-16-23/h5-10,13-16,20-21H,17-19H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	530	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]pirenzepine from muscarinic M1 receptor of rat cortex homogenates.				Bioorg Med Chem Lett 7: 979-984 (1997) Article DOI: 10.1016/S0960-894X(97)00143-1 BindingDB Entry DOI: 10.7270/Q2N29XFM
					More data for this Ligand-Target Pair