BDBM50291989 (S)-2-Amino-N-(2,6-dimethyl-phenyl)-propionamide(tocainide)::(S)-2-amino-N-(2,6-dimethylphenyl)propanamide::CHEMBL387108::S-TOCAINIDE::TOCAINIDE

SMILES: C[C@H](N)C(=O)Nc1c(C)cccc1C

InChI Key: InChIKey=BUJAGSGYPOAWEI-VIFPVBQESA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50291989   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 4 subunit alpha (Homo sapiens (Human))	BDBM50291989 ((S)-2-Amino-N-(2,6-dimethyl-phenyl)-propionamide(t...) Show SMILES C[C@H](N)C(=O)Nc1c(C)cccc1C |r| Show InChI InChI=1S/C11H16N2O/c1-7-5-4-6-8(2)10(7)13-11(14)9(3)12/h4-6,9H,12H2,1-3H3,(H,13,14)/t9-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.24E+5	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari Curated by ChEMBL					Assay Description Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium current				Eur J Med Chem 44: 1477-85 (2009) Article DOI: 10.1016/j.ejmech.2008.10.005 BindingDB Entry DOI: 10.7270/Q2M61MGC
					More data for this Ligand-Target Pair