BDBM50292388 3,9-dihydroxy-2,10-diprenylpterocap-6a-ene::CHEMBL462699
SMILES: [#6]\[#6](-[#6])=[#6]\[#6]-c1cc2-c3oc4c(-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])ccc4c3-[#6]-[#8]-c2cc1-[#8]
InChI Key: InChIKey=VNTSSLCFFUCTNP-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phospholipase A2 (Homo sapiens (Human)) | BDBM50292388 (3,9-dihydroxy-2,10-diprenylpterocap-6a-ene | CHEMB...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of PLA2 in fMLP and A23187 ionophore-stimulated human HL60 cells assessed as effect on [3H]arachidonic acid release | J Nat Prod 60: 537-539 (1997) Article DOI: 10.1021/np960533e BindingDB Entry DOI: 10.7270/Q21G0M8S | |||||||||||
More data for this Ligand-Target Pair |