BDBM50292478 (2S,4S)-5,8-dimethoxy-6-methyl-4-phenyl-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid::CHEMBL453823

SMILES: COc1cc(C)c(OC)c2[C@@H](C[C@@H](Cc12)C(O)=O)c1ccccc1

InChI Key: InChIKey=HVWXAXKJRJHQDH-GJZGRUSLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50292478   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50292478 ((2S,4S)-5,8-dimethoxy-6-methyl-4-phenyl-1,2,3,4-te...) Show SMILES COc1cc(C)c(OC)c2[C@@H](C[C@@H](Cc12)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C20H22O4/c1-12-9-17(23-2)16-11-14(20(21)22)10-15(18(16)19(12)24-3)13-7-5-4-6-8-13/h4-9,14-15H,10-11H2,1-3H3,(H,21,22)/t14-,15-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	1.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [125I]endothelin-1 from human recombinant ETA receptor expressed in CHO cells				J Nat Prod 58: 1515-1520 (1995) Article DOI: 10.1021/np50124a006 BindingDB Entry DOI: 10.7270/Q2ST7PV5
					More data for this Ligand-Target Pair