BDBM50292522 2-(3,5-dihydroxyphenyl)ethene-1,1,2-tricarbonitrile::CHEMBL454002

SMILES: [#8]-c1cc(-[#8])cc(c1)-[#6](\C#N)=[#6](\C#N)C#N

InChI Key: InChIKey=GQUWDIOBISABKQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50292522   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50292522 (2-(3,5-dihydroxyphenyl)ethene-1,1,2-tricarbonitril...) Show SMILES [#8]-c1cc(-[#8])cc(c1)-[#6](\C#N)=[#6](\C#N)C#N Show InChI InChI=1S/C11H5N3O2/c12-4-8(5-13)11(6-14)7-1-9(15)3-10(16)2-7/h1-3,15-16H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of EGFR in human A431 cells				J Nat Prod 55: 1529-1560 (1992) Article DOI: 10.1021/np50089a001 BindingDB Entry DOI: 10.7270/Q2J966CC
					More data for this Ligand-Target Pair