BDBM50292603 2-(pyrrolidin-1-yl)ethyl 10H-phenothiazine-10-carboxylate::CHEMBL481153

SMILES: O=C(OCCN1CCCC1)N1c2ccccc2Sc2ccccc12

InChI Key: InChIKey=CJGNMVAAMQAWEF-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50292603   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Homo sapiens (Human))	BDBM50292603 (2-(pyrrolidin-1-yl)ethyl 10H-phenothiazine-10-carb...) Show SMILES O=C(OCCN1CCCC1)N1c2ccccc2Sc2ccccc12 Show InChI InChI=1S/C19H20N2O2S/c22-19(23-14-13-20-11-5-6-12-20)21-15-7-1-3-9-17(15)24-18-10-4-2-8-16(18)21/h1-4,7-10H,5-6,11-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dalhousie University Curated by ChEMBL					Assay Description Antagonist activity at histamine H1 receptor (unknown origin) by PDSP assay				Bioorg Med Chem Lett 23: 3822-5 (2013) Article DOI: 10.1016/j.bmcl.2013.04.082 BindingDB Entry DOI: 10.7270/Q2H133DC
					More data for this Ligand-Target Pair
Histamine H2 Receptor (Homo sapiens (Human))	BDBM50292603 (2-(pyrrolidin-1-yl)ethyl 10H-phenothiazine-10-carb...) Show SMILES O=C(OCCN1CCCC1)N1c2ccccc2Sc2ccccc12 Show InChI InChI=1S/C19H20N2O2S/c22-19(23-14-13-20-11-5-6-12-20)21-15-7-1-3-9-17(15)24-18-10-4-2-8-16(18)21/h1-4,7-10H,5-6,11-14H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dalhousie University Curated by ChEMBL					Assay Description Antagonist activity at histamine H2 receptor (unknown origin) by PDSP assay				Bioorg Med Chem Lett 23: 3822-5 (2013) Article DOI: 10.1016/j.bmcl.2013.04.082 BindingDB Entry DOI: 10.7270/Q2H133DC
					More data for this Ligand-Target Pair
Cholinesterases (Homo sapiens (Human))	BDBM50292603 (2-(pyrrolidin-1-yl)ethyl 10H-phenothiazine-10-carb...) Show SMILES O=C(OCCN1CCCC1)N1c2ccccc2Sc2ccccc12 Show InChI InChI=1S/C19H20N2O2S/c22-19(23-14-13-20-11-5-6-12-20)21-15-7-1-3-9-17(15)24-18-10-4-2-8-16(18)21/h1-4,7-10H,5-6,11-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	650	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dalhousie University Curated by ChEMBL					Assay Description Inhibition of human serum BchE by Ellman's assay				J Med Chem 51: 4200-12 (2008) Article DOI: 10.1021/jm8002075 BindingDB Entry DOI: 10.7270/Q24J0DXF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Homo sapiens (Human))	BDBM50292603 (2-(pyrrolidin-1-yl)ethyl 10H-phenothiazine-10-carb...) Show SMILES O=C(OCCN1CCCC1)N1c2ccccc2Sc2ccccc12 Show InChI InChI=1S/C19H20N2O2S/c22-19(23-14-13-20-11-5-6-12-20)21-15-7-1-3-9-17(15)24-18-10-4-2-8-16(18)21/h1-4,7-10H,5-6,11-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dalhousie University Curated by ChEMBL					Assay Description Antagonist activity at serotonin 5HT3 receptor (unknown origin) by PDSP assay				Bioorg Med Chem Lett 23: 3822-5 (2013) Article DOI: 10.1016/j.bmcl.2013.04.082 BindingDB Entry DOI: 10.7270/Q2H133DC
					More data for this Ligand-Target Pair