BDBM50292627 (RS)-9-chloro-6-(2-chlorophenyl)-4-hydroxy-2,5-diazabicyclo[5.4.0]undeca-5,8,10,12-tetraen-3-one::7-Chloro-5-(2-chloro-phenyl)-3-hydroxy-1,3-dihydro-benzo[e][1,4]diazepin-2-one::7-Chloro-5-(2-chloro-phenyl)-3-hydroxy-1,3-dihydro-benzo[e][1,4]diazepin-2-one (lorazepam)::7-chloro-5-(2-chlorophenyl)-3-hydroxy-1H-benzo[e][1,4]diazepin-2(3H)-one::Ativan::CHEMBL580::LORAZEPAM::LORAZEPAM7-Chloro-5-(2-chloro-phenyl)-3-hydroxy-1,3-dihydro-benzo[e][1,4]diazepin-2-one::Loraz::Lorazepam intensol::Lorazepam preservative free::WY-4036
SMILES: OC1N=C(c2ccccc2Cl)c2cc(Cl)ccc2NC1=O
InChI Key: InChIKey=DIWRORZWFLOCLC-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Liver fatty acid binding protein (rat L-FABP) (Rattus norvegicus (Rat)) | BDBM50292627 ((RS)-9-chloro-6-(2-chlorophenyl)-4-hydroxy-2,5-dia...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | Article PubMed | 1.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Monash University (Parkville Campus) Curated by ChEMBL | Assay Description Displacement of 1-anilinonaphthalene-8-sulphonic acid from rat recombinant L-FABP high binding affinity site expressed in Escherichia coli BL21 by co... | J Med Chem 51: 3755-64 (2008) Article DOI: 10.1021/jm701192w BindingDB Entry DOI: 10.7270/Q2KH0P7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver fatty acid binding protein (rat L-FABP) (Rattus norvegicus (Rat)) | BDBM50292627 ((RS)-9-chloro-6-(2-chlorophenyl)-4-hydroxy-2,5-dia...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | Article PubMed | 1.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Monash University (Parkville Campus) Curated by ChEMBL | Assay Description Displacement of 1-anilinonaphthalene-8-sulphonic acid from rat recombinant L-FABP low binding affinity site expressed in Escherichia coli BL21 by com... | J Med Chem 51: 3755-64 (2008) Article DOI: 10.1021/jm701192w BindingDB Entry DOI: 10.7270/Q2KH0P7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Translocator protein (Homo sapiens (Human)) | BDBM50292627 ((RS)-9-chloro-6-(2-chlorophenyl)-4-hydroxy-2,5-dia...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | 3.50E+9 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard University Curated by ChEMBL | Assay Description Binding affinity of compound towards Benzodiazepine receptor in a competition assay | J Med Chem 39: 5246-56 (1997) Article DOI: 10.1021/jm960536o BindingDB Entry DOI: 10.7270/Q2NG4RTQ | |||||||||||
More data for this Ligand-Target Pair |