BDBM50292685 (1R,2S)-N2-hydroxy-1-(4-((2-phenylquinolin-4-yl)methoxy)benzyl)-N1-(piperidin-4-ylmethyl)cyclopropane-1,2-dicarboxamide::CHEMBL452212

SMILES: ONC(=O)[C@H]1C[C@]1(Cc1ccc(OCc2cc(nc3ccccc23)-c2ccccc2)cc1)C(=O)NCC1CCNCC1

InChI Key: InChIKey=LZHATKQUQHRBAF-SJHOIFEDSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50292685   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50292685 ((1R,2S)-N2-hydroxy-1-(4-((2-phenylquinolin-4-yl)me...) Show SMILES ONC(=O)[C@H]1C[C@]1(Cc1ccc(OCc2cc(nc3ccccc23)-c2ccccc2)cc1)C(=O)NCC1CCNCC1 |r| Show InChI InChI=1S/C34H36N4O4/c39-32(38-41)29-20-34(29,33(40)36-21-24-14-16-35-17-15-24)19-23-10-12-27(13-11-23)42-22-26-18-31(25-6-2-1-3-7-25)37-30-9-5-4-8-28(26)30/h1-13,18,24,29,35,41H,14-17,19-22H2,(H,36,40)(H,38,39)/t29-,34+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant TACE				Bioorg Med Chem Lett 18: 5809-14 (2009) Article DOI: 10.1016/j.bmcl.2008.09.045 BindingDB Entry DOI: 10.7270/Q2N29WZX
					More data for this Ligand-Target Pair