null
SMILES: CCc1cc2nccc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\C
InChI Key: InChIKey=CANSHISPWMMZOH-HWKANZROSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50292741 (CHEMBL490687 | N-(4-(3-chloro-4-fluorophenylamino)...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Inhibition of human recombinant EGFR | J Med Chem 52: 964-75 (2009) Article DOI: 10.1021/jm800829v BindingDB Entry DOI: 10.7270/Q27W6C7Q | |||||||||||
More data for this Ligand-Target Pair |