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SMILES: CCOC(=O)c1ccc(N2CCOCC2)c(NS(=O)(=O)c2cc(Br)c(Cl)s2)c1

InChI Key: InChIKey=QNBDIJUSIIMDQQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50292743   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50292743
PNG
(CHEMBL461782 | ethyl 3-(4-bromo-5-chlorothiophene-...)
Show SMILES CCOC(=O)c1ccc(N2CCOCC2)c(NS(=O)(=O)c2cc(Br)c(Cl)s2)c1
Show InChI InChI=1S/C17H18BrClN2O5S2/c1-2-26-17(22)11-3-4-14(21-5-7-25-8-6-21)13(9-11)20-28(23,24)15-10-12(18)16(19)27-15/h3-4,9-10,20H,2,5-8H2,1H3
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.11E+4n/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Inhibition of human recombinant EGFR

J Med Chem 52: 964-75 (2009)


Article DOI: 10.1021/jm800829v
BindingDB Entry DOI: 10.7270/Q27W6C7Q
More data for this
Ligand-Target Pair