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SMILES: OC[C@@H](O)CN(Cc1c[nH]c2c1nc[nH]c2=O)Cc1ccccc1

InChI Key: InChIKey=WBNKKFGASWUKMH-AWEZNQCLSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293084   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Purine nucleoside phosphorylase


(Homo sapiens (Human))		BDBM50293084
PNG
(7-({Benzyl[(2R)-2,3-dihydroxypropyl]amino}methyl)-...)
Show SMILES OC[C@@H](O)CN(Cc1c[nH]c2c1nc[nH]c2=O)Cc1ccccc1 |r|
Show InChI InChI=1S/C17H20N4O3/c22-10-14(23)9-21(7-12-4-2-1-3-5-12)8-13-6-18-16-15(13)19-11-20-17(16)24/h1-6,11,14,18,22-23H,7-10H2,(H,19,20,24)/t14-/m0/s1
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Article
PubMed
 3.00E+5n/an/an/an/an/an/an/an/a



Industrial Research Limited

Curated by ChEMBL


Assay Description
Inhibition of human PNP by xanthine-oxidase coupled assay

J Med Chem 52: 1126-43 (2009)


Article DOI: 10.1021/jm801421q
BindingDB Entry DOI: 10.7270/Q2QR4Z18
More data for this
Ligand-Target Pair