BDBM50293107 5-(4-fluorophenyl)-3-m-tolyl-1,2,4-oxadiazole::CHEMBL472839::cid_888120
SMILES: Cc1cccc(c1)-c1noc(n1)-c1ccc(F)cc1
InChI Key: InChIKey=MZWKUYWUBBRDEQ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Nuclear factor NF-kappa-B (Homo sapiens (Human)) | BDBM50293107 (5-(4-fluorophenyl)-3-m-tolyl-1,2,4-oxadiazole | CH...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 1.05E+5 | n/a | n/a | n/a | n/a |
SRMLSC Curated by PubChem BioAssay | Assay Description Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q27P8WT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Luciferin 4-monooxygenase (Photinus pyralis) | BDBM50293107 (5-(4-fluorophenyl)-3-m-tolyl-1,2,4-oxadiazole | CH...) | PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health Curated by ChEMBL | Assay Description Inhibition of luciferin binding site of Photinus pyralis luciferase by noncompetitive inhibition assay | J Med Chem 52: 1450-8 (2010) Article DOI: 10.1021/jm8014525 BindingDB Entry DOI: 10.7270/Q2XD11PW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Luciferin 4-monooxygenase (Photuris pennsylvanica) | BDBM50293107 (5-(4-fluorophenyl)-3-m-tolyl-1,2,4-oxadiazole | CH...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 580 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health Curated by ChEMBL | Assay Description Inhibition of luciferin binding site of Photuris pennsylvanica luciferase by noncompetitive inhibition assay | J Med Chem 52: 1450-8 (2010) Article DOI: 10.1021/jm8014525 BindingDB Entry DOI: 10.7270/Q2XD11PW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Luciferin 4-monooxygenase (Photuris pennsylvanica) | BDBM50293107 (5-(4-fluorophenyl)-3-m-tolyl-1,2,4-oxadiazole | CH...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health Curated by ChEMBL | Assay Description Inhibition of luciferin binding site of Photuris pennsylvanica luciferase by noncompetitive KinaseGlo luminescent assay | J Med Chem 52: 1450-8 (2010) Article DOI: 10.1021/jm8014525 BindingDB Entry DOI: 10.7270/Q2XD11PW | |||||||||||
More data for this Ligand-Target Pair |