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BDBM50293186 4-methyl-2-((4-(morpholinomethyl)phenoxy)methyl)morpholine::CHEMBL447516

SMILES: CN1CCOC(COc2ccc(CN3CCOCC3)cc2)C1

InChI Key: InChIKey=NVSNIJXGSXXZLS-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293186   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50293186
PNG
(4-methyl-2-((4-(morpholinomethyl)phenoxy)methyl)mo...)
Show SMILES CN1CCOC(COc2ccc(CN3CCOCC3)cc2)C1
Show InChI InChI=1S/C17H26N2O3/c1-18-6-11-21-17(13-18)14-22-16-4-2-15(3-5-16)12-19-7-9-20-10-8-19/h2-5,17H,6-14H2,1H3
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Article
PubMed
 2.10E+3n/an/an/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research& Development L.L.C.

Curated by ChEMBL


Assay Description
Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells

Bioorg Med Chem Lett 18: 5796-9 (2009)


Article DOI: 10.1016/j.bmcl.2008.09.077
BindingDB Entry DOI: 10.7270/Q2154H28
More data for this
Ligand-Target Pair