BDBM50293188 4-cyclobutyl-2-((4-(morpholinomethyl)phenoxy)methyl)morpholine::CHEMBL496554

SMILES: C(Oc1ccc(CN2CCOCC2)cc1)C1CN(CCO1)C1CCC1

InChI Key: InChIKey=LKJMWTSWMDOVIJ-UHFFFAOYSA-N

Data: 2 KI  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293188   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293188 (4-cyclobutyl-2-((4-(morpholinomethyl)phenoxy)methy...) Show SMILES C(Oc1ccc(CN2CCOCC2)cc1)C1CN(CCO1)C1CCC1 Show InChI InChI=1S/C20H30N2O3/c1-2-18(3-1)22-10-13-24-20(15-22)16-25-19-6-4-17(5-7-19)14-21-8-11-23-12-9-21/h4-7,18,20H,1-3,8-16H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50293188 (4-cyclobutyl-2-((4-(morpholinomethyl)phenoxy)methy...) Show SMILES C(Oc1ccc(CN2CCOCC2)cc1)C1CN(CCO1)C1CCC1 Show InChI InChI=1S/C20H30N2O3/c1-2-18(3-1)22-10-13-24-20(15-22)16-25-19-6-4-17(5-7-19)14-21-8-11-23-12-9-21/h4-7,18,20H,1-3,8-16H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from rat recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50293188 (4-cyclobutyl-2-((4-(morpholinomethyl)phenoxy)methy...) Show SMILES C(Oc1ccc(CN2CCOCC2)cc1)C1CN(CCO1)C1CCC1 Show InChI InChI=1S/C20H30N2O3/c1-2-18(3-1)22-10-13-24-20(15-22)16-25-19-6-4-17(5-7-19)14-21-8-11-23-12-9-21/h4-7,18,20H,1-3,8-16H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	19.1	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity rat recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair