BDBM50293355 CHEMBL538710::N-Hydroxy-E-3-(4'-cyanobiphenyl-4-yl)-acrylamide

SMILES: ONC(=O)\C=C\c1ccc(cc1)-c1ccc(cc1)C#N

InChI Key: InChIKey=NJUOLWKIAIFTKT-BJMVGYQFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293355   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50293355 (CHEMBL538710 | N-Hydroxy-E-3-(4'-cyanobiphenyl-4-y...) Show SMILES ONC(=O)\C=C\c1ccc(cc1)-c1ccc(cc1)C#N Show InChI InChI=1S/C16H12N2O2/c17-11-13-3-8-15(9-4-13)14-6-1-12(2-7-14)5-10-16(19)18-20/h1-10,20H,(H,18,19)/b10-5+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Milano Curated by ChEMBL					Assay Description Inhibition of HDAC2 in human HeLa cells				Eur J Med Chem 44: 1900-12 (2009) Article DOI: 10.1016/j.ejmech.2008.11.005 BindingDB Entry DOI: 10.7270/Q2M045G2
					More data for this Ligand-Target Pair