BDBM50293386 CHEMBL554824::{(3S)-5-[2-({4-[Amino(imino)methyl]benzyl}amino)-2-oxoethyl]-3-[benzylsulfonylamino]-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-7-yl}-propanoic acid, trifluoroacetate
SMILES: NC(=N)c1ccc(CNC(=O)CN2c3cc(CCC(O)=O)ccc3SC[C@@H](NS(=O)(=O)Cc3ccccc3)C2=O)cc1
InChI Key: InChIKey=QRFLSLZVPXHHCL-HSZRJFAPSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prothrombin (Homo sapiens (Human)) | BDBM50293386 (CHEMBL554824 | {(3S)-5-[2-({4-[Amino(imino)methyl]...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1 Curated by ChEMBL | Assay Description Inhibition of human factor 2a by spectrophotometry | Bioorg Med Chem Lett 19: 1386-91 (2009) Article DOI: 10.1016/j.bmcl.2009.01.039 BindingDB Entry DOI: 10.7270/Q2G73DRB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII/tissue factor (Homo sapiens (Human)) | BDBM50293386 (CHEMBL554824 | {(3S)-5-[2-({4-[Amino(imino)methyl]...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1 Curated by ChEMBL | Assay Description Inhibition of human tissue factor/factor 7a | Bioorg Med Chem Lett 19: 1386-91 (2009) Article DOI: 10.1016/j.bmcl.2009.01.039 BindingDB Entry DOI: 10.7270/Q2G73DRB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50293386 (CHEMBL554824 | {(3S)-5-[2-({4-[Amino(imino)methyl]...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier 1 Curated by ChEMBL | Assay Description Inhibition of human factor 10a by spectrometry | Bioorg Med Chem Lett 19: 1386-91 (2009) Article DOI: 10.1016/j.bmcl.2009.01.039 BindingDB Entry DOI: 10.7270/Q2G73DRB | |||||||||||
More data for this Ligand-Target Pair |