BDBM50293557 (R)-N[3-phenyl-3-(4'-(4-toluoyl)phenoxy)-propyl]sarcosine::CHEMBL551223
SMILES: CN(CC[C@@H](Oc1ccc(cc1)C(=O)c1ccc(C)cc1)c1ccccc1)CC(O)=O
InChI Key: InChIKey=HNBKNDFZJLEZLZ-XMMPIXPASA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glycine transporter 1 (Homo sapiens (Human)) | BDBM50293557 ((R)-N[3-phenyl-3-(4'-(4-toluoyl)phenoxy)-propyl]sa...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Binding affinity to GlyT1 | Bioorg Med Chem Lett 19: 2974-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.035 BindingDB Entry DOI: 10.7270/Q2F76CKH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycine transporter 2 (Homo sapiens (Human)) | BDBM50293557 ((R)-N[3-phenyl-3-(4'-(4-toluoyl)phenoxy)-propyl]sa...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]glycine from GlyT2 | Bioorg Med Chem Lett 19: 2974-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.035 BindingDB Entry DOI: 10.7270/Q2F76CKH | |||||||||||
More data for this Ligand-Target Pair |