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BDBM50293737 CHEMBL559960::N-(6-methoxypyrimidin-4-yl)picolinamide

SMILES: COc1cc(NC(=O)c2ccccn2)ncn1

InChI Key: InChIKey=ASKVSPFHGNOKGP-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293737   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 4 (mGluR4)


(Homo sapiens (Human))
BDBM50293737
PNG
(CHEMBL559960 | N-(6-methoxypyrimidin-4-yl)picolina...)
Show SMILES COc1cc(NC(=O)c2ccccn2)ncn1
Show InChI InChI=1S/C11H10N4O2/c1-17-10-6-9(13-7-14-10)15-11(16)8-4-2-3-5-12-8/h2-7H,1H3,(H,13,14,15,16)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Activity at human mGluR4 receptor expressed in CHO cells assessed as effect on calcium mobilization


J Med Chem 52: 4115-8 (2009)


Article DOI: 10.1021/jm9005065
BindingDB Entry DOI: 10.7270/Q2RJ4JHT
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGlu4)


(Rattus norvegicus (Rat))
BDBM50293737
PNG
(CHEMBL559960 | N-(6-methoxypyrimidin-4-yl)picolina...)
Show SMILES COc1cc(NC(=O)c2ccccn2)ncn1
Show InChI InChI=1S/C11H10N4O2/c1-17-10-6-9(13-7-14-10)15-11(16)8-4-2-3-5-12-8/h2-7H,1H3,(H,13,14,15,16)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Activity at rat mGluR4 receptor expressed in HEK293 cells assessed as effect on thallium flux


J Med Chem 52: 4115-8 (2009)


Article DOI: 10.1021/jm9005065
BindingDB Entry DOI: 10.7270/Q2RJ4JHT
More data for this
Ligand-Target Pair