BDBM50293745 2-(4-sulfamoylphenylamino)-1-(1-(2-(trifluoromethyl)phenyl)ethyl)-1H-benzo[d]imidazole-5-carboxamide::CHEMBL552298

SMILES: CC(c1ccccc1C(F)(F)F)n1c(Nc2ccc(cc2)S(N)(=O)=O)nc2cc(ccc12)C(N)=O

InChI Key: InChIKey=MBTCJFAQKYTMFO-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293745   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50293745 (2-(4-sulfamoylphenylamino)-1-(1-(2-(trifluoromethy...) Show SMILES CC(c1ccccc1C(F)(F)F)n1c(Nc2ccc(cc2)S(N)(=O)=O)nc2cc(ccc12)C(N)=O Show InChI InChI=1S/C23H20F3N5O3S/c1-13(17-4-2-3-5-18(17)23(24,25)26)31-20-11-6-14(21(27)32)12-19(20)30-22(31)29-15-7-9-16(10-8-15)35(28,33)34/h2-13H,1H3,(H2,27,32)(H,29,30)(H2,28,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of human kinesin spindle protein by endpoint assay				Bioorg Med Chem Lett 19: 3405-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.040 BindingDB Entry DOI: 10.7270/Q2MS3SS3
					More data for this Ligand-Target Pair
Kinesin heavy chain isoform 5A (Homo sapiens (Human))	BDBM50293745 (2-(4-sulfamoylphenylamino)-1-(1-(2-(trifluoromethy...) Show SMILES CC(c1ccccc1C(F)(F)F)n1c(Nc2ccc(cc2)S(N)(=O)=O)nc2cc(ccc12)C(N)=O Show InChI InChI=1S/C23H20F3N5O3S/c1-13(17-4-2-3-5-18(17)23(24,25)26)31-20-11-6-14(21(27)32)12-19(20)30-22(31)29-15-7-9-16(10-8-15)35(28,33)34/h2-13H,1H3,(H2,27,32)(H,29,30)(H2,28,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of nKHC				Bioorg Med Chem Lett 19: 3405-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.040 BindingDB Entry DOI: 10.7270/Q2MS3SS3
					More data for this Ligand-Target Pair
Kinesin-like protein KIF3B (Homo sapiens (Human))	BDBM50293745 (2-(4-sulfamoylphenylamino)-1-(1-(2-(trifluoromethy...) Show SMILES CC(c1ccccc1C(F)(F)F)n1c(Nc2ccc(cc2)S(N)(=O)=O)nc2cc(ccc12)C(N)=O Show InChI InChI=1S/C23H20F3N5O3S/c1-13(17-4-2-3-5-18(17)23(24,25)26)31-20-11-6-14(21(27)32)12-19(20)30-22(31)29-15-7-9-16(10-8-15)35(28,33)34/h2-13H,1H3,(H2,27,32)(H,29,30)(H2,28,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of Kif3B				Bioorg Med Chem Lett 19: 3405-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.040 BindingDB Entry DOI: 10.7270/Q2MS3SS3
					More data for this Ligand-Target Pair