Found 3 hits for monomerid = 50293757 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Kinesin-like protein KIF11
(Homo sapiens (Human)) | BDBM50293757
(2-(4-sulfamoylphenylamino)-1-(2-(trifluoromethyl)b...)Show SMILES NS(=O)(=O)c1ccc(Nc2nc3cc(ccc3n2Cc2ccccc2C(F)(F)F)C(O)=O)cc1 Show InChI InChI=1S/C22H17F3N4O4S/c23-22(24,25)17-4-2-1-3-14(17)12-29-19-10-5-13(20(30)31)11-18(19)28-21(29)27-15-6-8-16(9-7-15)34(26,32)33/h1-11H,12H2,(H,27,28)(H,30,31)(H2,26,32,33) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human kinesin spindle protein by endpoint assay |
Bioorg Med Chem Lett 19: 3405-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.040 BindingDB Entry DOI: 10.7270/Q2MS3SS3 |
More data for this Ligand-Target Pair | |
Kinesin heavy chain isoform 5A
(Homo sapiens (Human)) | BDBM50293757
(2-(4-sulfamoylphenylamino)-1-(2-(trifluoromethyl)b...)Show SMILES NS(=O)(=O)c1ccc(Nc2nc3cc(ccc3n2Cc2ccccc2C(F)(F)F)C(O)=O)cc1 Show InChI InChI=1S/C22H17F3N4O4S/c23-22(24,25)17-4-2-1-3-14(17)12-29-19-10-5-13(20(30)31)11-18(19)28-21(29)27-15-6-8-16(9-7-15)34(26,32)33/h1-11H,12H2,(H,27,28)(H,30,31)(H2,26,32,33) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Inhibition of nKHC |
Bioorg Med Chem Lett 19: 3405-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.040 BindingDB Entry DOI: 10.7270/Q2MS3SS3 |
More data for this Ligand-Target Pair | |
Kinesin-like protein KIF3B
(Homo sapiens (Human)) | BDBM50293757
(2-(4-sulfamoylphenylamino)-1-(2-(trifluoromethyl)b...)Show SMILES NS(=O)(=O)c1ccc(Nc2nc3cc(ccc3n2Cc2ccccc2C(F)(F)F)C(O)=O)cc1 Show InChI InChI=1S/C22H17F3N4O4S/c23-22(24,25)17-4-2-1-3-14(17)12-29-19-10-5-13(20(30)31)11-18(19)28-21(29)27-15-6-8-16(9-7-15)34(26,32)33/h1-11H,12H2,(H,27,28)(H,30,31)(H2,26,32,33) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Kif3B |
Bioorg Med Chem Lett 19: 3405-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.040 BindingDB Entry DOI: 10.7270/Q2MS3SS3 |
More data for this Ligand-Target Pair | |