BDBM50293764 CHEMBL549531::methyl 2-(4-(methylthio)phenylamino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxylate
SMILES: COC(=O)c1ccc2n(Cc3ccccc3C(F)(F)F)c(Nc3ccc(SC)cc3)nc2c1
InChI Key: InChIKey=CJDPIIDPHBOQDC-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kinesin-like protein KIF11 (Homo sapiens (Human)) | BDBM50293764 (CHEMBL549531 | methyl 2-(4-(methylthio)phenylamino...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.34E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of human kinesin spindle protein by endpoint assay | Bioorg Med Chem Lett 19: 3405-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.040 BindingDB Entry DOI: 10.7270/Q2MS3SS3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin heavy chain isoform 5A (Homo sapiens (Human)) | BDBM50293764 (CHEMBL549531 | methyl 2-(4-(methylthio)phenylamino...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of nKHC | Bioorg Med Chem Lett 19: 3405-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.040 BindingDB Entry DOI: 10.7270/Q2MS3SS3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF3B (Homo sapiens (Human)) | BDBM50293764 (CHEMBL549531 | methyl 2-(4-(methylthio)phenylamino...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of Kif3B | Bioorg Med Chem Lett 19: 3405-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.040 BindingDB Entry DOI: 10.7270/Q2MS3SS3 | |||||||||||
More data for this Ligand-Target Pair |