BDBM50293776 2-(2-morpholinoethylamino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxylic acid::CHEMBL549873

SMILES: OC(=O)c1ccc2n(Cc3ccccc3C(F)(F)F)c(NCCN3CCOCC3)nc2c1

InChI Key: InChIKey=MHBGCUBZCUWUDL-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293776   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kinesin-like protein 1 (Homo sapiens (Human))	BDBM50293776 (2-(2-morpholinoethylamino)-1-(2-(trifluoromethyl)b...) Show SMILES OC(=O)c1ccc2n(Cc3ccccc3C(F)(F)F)c(NCCN3CCOCC3)nc2c1 Show InChI InChI=1S/C22H23F3N4O3/c23-22(24,25)17-4-2-1-3-16(17)14-29-19-6-5-15(20(30)31)13-18(19)27-21(29)26-7-8-28-9-11-32-12-10-28/h1-6,13H,7-12,14H2,(H,26,27)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of human kinesin spindle protein by endpoint assay				Bioorg Med Chem Lett 19: 3405-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.040 BindingDB Entry DOI: 10.7270/Q2MS3SS3
					More data for this Ligand-Target Pair
Kinesin heavy chain isoform 5A (Homo sapiens (Human))	BDBM50293776 (2-(2-morpholinoethylamino)-1-(2-(trifluoromethyl)b...) Show SMILES OC(=O)c1ccc2n(Cc3ccccc3C(F)(F)F)c(NCCN3CCOCC3)nc2c1 Show InChI InChI=1S/C22H23F3N4O3/c23-22(24,25)17-4-2-1-3-16(17)14-29-19-6-5-15(20(30)31)13-18(19)27-21(29)26-7-8-28-9-11-32-12-10-28/h1-6,13H,7-12,14H2,(H,26,27)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of nKHC				Bioorg Med Chem Lett 19: 3405-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.040 BindingDB Entry DOI: 10.7270/Q2MS3SS3
					More data for this Ligand-Target Pair
Kinesin-like protein KIF3B (Homo sapiens (Human))	BDBM50293776 (2-(2-morpholinoethylamino)-1-(2-(trifluoromethyl)b...) Show SMILES OC(=O)c1ccc2n(Cc3ccccc3C(F)(F)F)c(NCCN3CCOCC3)nc2c1 Show InChI InChI=1S/C22H23F3N4O3/c23-22(24,25)17-4-2-1-3-16(17)14-29-19-6-5-15(20(30)31)13-18(19)27-21(29)26-7-8-28-9-11-32-12-10-28/h1-6,13H,7-12,14H2,(H,26,27)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of Kif3B				Bioorg Med Chem Lett 19: 3405-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.040 BindingDB Entry DOI: 10.7270/Q2MS3SS3
					More data for this Ligand-Target Pair