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SMILES: Nc1nc2N(CCOCP(O)(O)=O)CNc2c(=S)[nH]1

InChI Key: InChIKey=FMFSJYMYNWKBLN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293827   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hypoxanthine-guanine phosphoribosyltransferase


(Homo sapiens (Human))		BDBM50293827
PNG
((2-(2-amino-6-thioxo-1,6,7,8-tetrahydropurin-9-yl)...)
Show SMILES Nc1nc2N(CCOCP(O)(O)=O)CNc2c(=S)[nH]1
Show InChI InChI=1S/C8H14N5O4PS/c9-8-11-6-5(7(19)12-8)10-3-13(6)1-2-17-4-18(14,15)16/h10H,1-4H2,(H2,14,15,16)(H3,9,11,12,19)
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Article
PubMed
>1.00E+6n/an/an/an/an/an/a7.4n/a



The University of Queensland

Curated by ChEMBL


Assay Description
Inhibition of human recombinant HGPRT at pH 7.4 by spectrophotometric assay

J Med Chem 52: 4391-9 (2009)


Article DOI: 10.1021/jm900267n
BindingDB Entry DOI: 10.7270/Q27M0809
More data for this
Ligand-Target Pair