BDBM50293835 (R)-5-(2-Amino-6-oxo-1,6,7,8-tetrahydro-purin-9-ylmethyl)-2-oxo-2lambda*5*-[1,4,2]dioxaphosphinan-2-ol anion::CHEMBL560829

SMILES: Nc1nc2N(C[C@@H]3COP(O)(=O)CO3)CNc2c(=O)[nH]1

InChI Key: InChIKey=KKWHQBVJXYTUHZ-RXMQYKEDSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293835   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50293835 ((R)-5-(2-Amino-6-oxo-1,6,7,8-tetrahydro-purin-9-yl...) Show SMILES Nc1nc2N(C[C@@H]3COP(O)(=O)CO3)CNc2c(=O)[nH]1 |r| Show InChI InChI=1S/C9H14N5O5P/c10-9-12-7-6(8(15)13-9)11-3-14(7)1-5-2-19-20(16,17)4-18-5/h5,11H,1-4H2,(H,16,17)(H3,10,12,13,15)/t5-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.23E+4	n/a	n/a	n/a	n/a	n/a	n/a	8.5	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of human recombinant HGPRT at pH 8.5 by spectrophotometric assay				J Med Chem 52: 4391-9 (2009) Article DOI: 10.1021/jm900267n BindingDB Entry DOI: 10.7270/Q27M0809
					More data for this Ligand-Target Pair				3D Structure (docked)
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human))	BDBM50293835 ((R)-5-(2-Amino-6-oxo-1,6,7,8-tetrahydro-purin-9-yl...) Show SMILES Nc1nc2N(C[C@@H]3COP(O)(=O)CO3)CNc2c(=O)[nH]1 |r| Show InChI InChI=1S/C9H14N5O5P/c10-9-12-7-6(8(15)13-9)11-3-14(7)1-5-2-19-20(16,17)4-18-5/h5,11H,1-4H2,(H,16,17)(H3,10,12,13,15)/t5-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of human recombinant HGPRT at pH 7.4 by spectrophotometric assay				J Med Chem 52: 4391-9 (2009) Article DOI: 10.1021/jm900267n BindingDB Entry DOI: 10.7270/Q27M0809
					More data for this Ligand-Target Pair				3D Structure (docked)