BDBM50293841 3-((3,5-dimethylisoxazol-4-yl)methoxy)-N-(4-methyl-3-(methylsulfonyl)phenyl)benzamide::CHEMBL558673

SMILES: Cc1noc(C)c1COc1cccc(c1)C(=O)Nc1ccc(C)c(c1)S(C)(=O)=O

InChI Key: InChIKey=SUQWCANQHRRQKR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293841   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ras-related C3 botulinum toxin substrate 1/T-lymphoma invasion and metastasis-inducing protein 1 (Homo sapiens (Human))	BDBM50293841 (3-((3,5-dimethylisoxazol-4-yl)methoxy)-N-(4-methyl...) Show SMILES Cc1noc(C)c1COc1cccc(c1)C(=O)Nc1ccc(C)c(c1)S(C)(=O)=O Show InChI InChI=1S/C21H22N2O5S/c1-13-8-9-17(11-20(13)29(4,25)26)22-21(24)16-6-5-7-18(10-16)27-12-19-14(2)23-28-15(19)3/h5-11H,12H2,1-4H3,(H,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of PDGF-BB-stimulated Rac1 activity in human aortic smooth muscle cells assessed as reduction of Rac1GTP level after 4 hrs by G-LISA				J Med Chem 52: 4087-90 (2009) Article DOI: 10.1021/jm8015987 BindingDB Entry DOI: 10.7270/Q23T9H81
					More data for this Ligand-Target Pair