BDBM50293860 (S)-2-(3-Benzoylphenyl)-N-(3,4-dihydroxyphenethyl)propanamide::CHEMBL560356

SMILES: C[C@H](C(=O)NCCc1ccc(O)c(O)c1)c1cccc(Oc2ccccc2)c1

InChI Key: InChIKey=CECXAXJMMNBDRN-INIZCTEOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293860   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Zinc finger protein GLI2 (Homo sapiens (Human))	BDBM50293860 ((S)-2-(3-Benzoylphenyl)-N-(3,4-dihydroxyphenethyl)...) Show SMILES C[C@H](C(=O)NCCc1ccc(O)c(O)c1)c1cccc(Oc2ccccc2)c1 |r| Show InChI InChI=1S/C23H23NO4/c1-16(23(27)24-13-12-17-10-11-21(25)22(26)14-17)18-6-5-9-20(15-18)28-19-7-3-2-4-8-19/h2-11,14-16,25-26H,12-13H2,1H3,(H,24,27)/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
St Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of exogenously transfected human Gli2 deltaN-mediated transcriptional activity in mouse C3H10T1/2 cells after 24 hrs by luciferase reporte...				J Med Chem 52: 4277-87 (2009) Article DOI: 10.1021/jm900106f BindingDB Entry DOI: 10.7270/Q2QJ7H9J
					More data for this Ligand-Target Pair
Zinc finger protein GLI1 (Homo sapiens (Human))	BDBM50293860 ((S)-2-(3-Benzoylphenyl)-N-(3,4-dihydroxyphenethyl)...) Show SMILES C[C@H](C(=O)NCCc1ccc(O)c(O)c1)c1cccc(Oc2ccccc2)c1 |r| Show InChI InChI=1S/C23H23NO4/c1-16(23(27)24-13-12-17-10-11-21(25)22(26)14-17)18-6-5-9-20(15-18)28-19-7-3-2-4-8-19/h2-11,14-16,25-26H,12-13H2,1H3,(H,24,27)/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
St Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of exogenously transfected human Gli1-mediated transcriptional activity in mouse C3H10T1/2 cells after 24 hrs by luciferase reporter gene ...				J Med Chem 52: 4277-87 (2009) Article DOI: 10.1021/jm900106f BindingDB Entry DOI: 10.7270/Q2QJ7H9J
					More data for this Ligand-Target Pair