null

SMILES: COc1ccccc1N1CCN(Cc2cc3ccccn3n2)CC1

InChI Key: InChIKey=PONADOYAURXJAH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50294117   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50294117 (2-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)H-pyr...) Show SMILES COc1ccccc1N1CCN(Cc2cc3ccccn3n2)CC1 Show InChI InChI=1S/C19H22N4O/c1-24-19-8-3-2-7-18(19)22-12-10-21(11-13-22)15-16-14-17-6-4-5-9-23(17)20-16/h2-9,14H,10-13,15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D4 receptor expressed in CHO cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50294117 (2-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)H-pyr...) Show SMILES COc1ccccc1N1CCN(Cc2cc3ccccn3n2)CC1 Show InChI InChI=1S/C19H22N4O/c1-24-19-8-3-2-7-18(19)22-12-10-21(11-13-22)15-16-14-17-6-4-5-9-23(17)20-16/h2-9,14H,10-13,15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from wild type human cloned dopamine D4 receptor expressed in HEK293 cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50294117 (2-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)H-pyr...) Show SMILES COc1ccccc1N1CCN(Cc2cc3ccccn3n2)CC1 Show InChI InChI=1S/C19H22N4O/c1-24-19-8-3-2-7-18(19)22-12-10-21(11-13-22)15-16-14-17-6-4-5-9-23(17)20-16/h2-9,14H,10-13,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in CHO cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50294117 (2-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)H-pyr...) Show SMILES COc1ccccc1N1CCN(Cc2cc3ccccn3n2)CC1 Show InChI InChI=1S/C19H22N4O/c1-24-19-8-3-2-7-18(19)22-12-10-21(11-13-22)15-16-14-17-6-4-5-9-23(17)20-16/h2-9,14H,10-13,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from wild type human cloned dopamine D2L receptor expressed in HEK293 cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50294117 (2-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)H-pyr...) Show SMILES COc1ccccc1N1CCN(Cc2cc3ccccn3n2)CC1 Show InChI InChI=1S/C19H22N4O/c1-24-19-8-3-2-7-18(19)22-12-10-21(11-13-22)15-16-14-17-6-4-5-9-23(17)20-16/h2-9,14H,10-13,15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	770	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from wild type human cloned dopamine D3 receptor expressed in HEK293 cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50294117 (2-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)H-pyr...) Show SMILES COc1ccccc1N1CCN(Cc2cc3ccccn3n2)CC1 Show InChI InChI=1S/C19H22N4O/c1-24-19-8-3-2-7-18(19)22-12-10-21(11-13-22)15-16-14-17-6-4-5-9-23(17)20-16/h2-9,14H,10-13,15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in CHO cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair