BDBM50294184 CHEMBL561640::N-(4-chlorophenyl)-2-phenoxypropanamide::N-(4-chlorophenyl)-2-phenoxypropanamide, A::N-(4-chlorophenyl)-2-phenoxypropanamide, Compound A

SMILES: CC(Oc1ccccc1)C(=O)Nc1ccc(Cl)cc1

InChI Key: InChIKey=HHNBSZFQIIWTAP-UHFFFAOYSA-N

Data: 8 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50294184   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inosine Monophosphate Dehydrogenase Type 1 (IMPDH1) (Homo sapiens (Human))	BDBM50294184 (CHEMBL561640 | N-(4-chlorophenyl)-2-phenoxypropana...) Show SMILES CC(Oc1ccccc1)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C15H14ClNO2/c1-11(19-14-5-3-2-4-6-14)15(18)17-13-9-7-12(16)8-10-13/h2-11H,1H3,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	8.0	25
Brandeis University					Assay Description Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.				Chem Biol 15: 70-7 (2008) Article DOI: 10.1016/j.chembiol.2007.12.010 BindingDB Entry DOI: 10.7270/Q2T1524X
					More data for this Ligand-Target Pair
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2) (Homo sapiens (Human))	BDBM50294184 (CHEMBL561640 | N-(4-chlorophenyl)-2-phenoxypropana...) Show SMILES CC(Oc1ccccc1)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C15H14ClNO2/c1-11(19-14-5-3-2-4-6-14)15(18)17-13-9-7-12(16)8-10-13/h2-11H,1H3,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	8.0	25
Brandeis University					Assay Description Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.				Chem Biol 15: 70-7 (2008) Article DOI: 10.1016/j.chembiol.2007.12.010 BindingDB Entry DOI: 10.7270/Q2T1524X
					More data for this Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH) (Cryptosporidium parvum)	BDBM50294184 (CHEMBL561640 | N-(4-chlorophenyl)-2-phenoxypropana...) Show SMILES CC(Oc1ccccc1)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C15H14ClNO2/c1-11(19-14-5-3-2-4-6-14)15(18)17-13-9-7-12(16)8-10-13/h2-11H,1H3,(H,17,18)	PDB MMDB B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	8.0	25
Brandeis University					Assay Description Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.				Chem Biol 15: 70-7 (2008) Article DOI: 10.1016/j.chembiol.2007.12.010 BindingDB Entry DOI: 10.7270/Q2T1524X
					More data for this Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH) (Cryptosporidium parvum)	BDBM50294184 (CHEMBL561640 | N-(4-chlorophenyl)-2-phenoxypropana...) Show SMILES CC(Oc1ccccc1)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C15H14ClNO2/c1-11(19-14-5-3-2-4-6-14)15(18)17-13-9-7-12(16)8-10-13/h2-11H,1H3,(H,17,18)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	8.0	25
Brandeis University					Assay Description Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).				Chem Biol 17: 1084-91 (2010) Article DOI: 10.1016/j.chembiol.2010.07.014 BindingDB Entry DOI: 10.7270/Q2GH9GF5
					More data for this Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH) (Helicobacter pylori (strain G27))	BDBM50294184 (CHEMBL561640 | N-(4-chlorophenyl)-2-phenoxypropana...) Show SMILES CC(Oc1ccccc1)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C15H14ClNO2/c1-11(19-14-5-3-2-4-6-14)15(18)17-13-9-7-12(16)8-10-13/h2-11H,1H3,(H,17,18)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	8.0	25
Brandeis University					Assay Description Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).				Chem Biol 17: 1084-91 (2010) Article DOI: 10.1016/j.chembiol.2010.07.014 BindingDB Entry DOI: 10.7270/Q2GH9GF5
					More data for this Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH) (Cryptosporidium parvum)	BDBM50294184 (CHEMBL561640 | N-(4-chlorophenyl)-2-phenoxypropana...) Show SMILES CC(Oc1ccccc1)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C15H14ClNO2/c1-11(19-14-5-3-2-4-6-14)15(18)17-13-9-7-12(16)8-10-13/h2-11H,1H3,(H,17,18)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli guaB assessed as NADH production by fluorescence assay				J Med Chem 52: 4623-30 (2009) Article DOI: 10.1021/jm900410u BindingDB Entry DOI: 10.7270/Q2HM59C1
					More data for this Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH) (Streptococcus pyogenes)	BDBM50294184 (CHEMBL561640 | N-(4-chlorophenyl)-2-phenoxypropana...) Show SMILES CC(Oc1ccccc1)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C15H14ClNO2/c1-11(19-14-5-3-2-4-6-14)15(18)17-13-9-7-12(16)8-10-13/h2-11H,1H3,(H,17,18)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.60E+4	n/a	n/a	n/a	n/a	8.0	25
Brandeis University					Assay Description Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).				Chem Biol 17: 1084-91 (2010) Article DOI: 10.1016/j.chembiol.2010.07.014 BindingDB Entry DOI: 10.7270/Q2GH9GF5
					More data for this Ligand-Target Pair
Inosine Monophosphate Dehydrogenase Type 1 (IMPDH1) (Homo sapiens (Human))	BDBM50294184 (CHEMBL561640 | N-(4-chlorophenyl)-2-phenoxypropana...) Show SMILES CC(Oc1ccccc1)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C15H14ClNO2/c1-11(19-14-5-3-2-4-6-14)15(18)17-13-9-7-12(16)8-10-13/h2-11H,1H3,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of human recombinant IMPDH1 expressed in Escherichia coli guaB assessed as NADH production by fluorescence assay				J Med Chem 52: 4623-30 (2009) Article DOI: 10.1021/jm900410u BindingDB Entry DOI: 10.7270/Q2HM59C1
					More data for this Ligand-Target Pair
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2) (Homo sapiens (Human))	BDBM50294184 (CHEMBL561640 | N-(4-chlorophenyl)-2-phenoxypropana...) Show SMILES CC(Oc1ccccc1)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C15H14ClNO2/c1-11(19-14-5-3-2-4-6-14)15(18)17-13-9-7-12(16)8-10-13/h2-11H,1H3,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of human recombinant IMPDH2 expressed in Escherichia coli guaB assessed as NADH production by fluorescence assay				J Med Chem 52: 4623-30 (2009) Article DOI: 10.1021/jm900410u BindingDB Entry DOI: 10.7270/Q2HM59C1
					More data for this Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH) (Cryptosporidium parvum)	BDBM50294184 (CHEMBL561640 | N-(4-chlorophenyl)-2-phenoxypropana...) Show SMILES CC(Oc1ccccc1)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C15H14ClNO2/c1-11(19-14-5-3-2-4-6-14)15(18)17-13-9-7-12(16)8-10-13/h2-11H,1H3,(H,17,18)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli TX685 assessed as NADH production by fluorescence assay in absen...				J Med Chem 52: 4623-30 (2009) Article DOI: 10.1021/jm900410u BindingDB Entry DOI: 10.7270/Q2HM59C1
					More data for this Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH) (Borrelia burgdorferi)	BDBM50294184 (CHEMBL561640 | N-(4-chlorophenyl)-2-phenoxypropana...) Show SMILES CC(Oc1ccccc1)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C15H14ClNO2/c1-11(19-14-5-3-2-4-6-14)15(18)17-13-9-7-12(16)8-10-13/h2-11H,1H3,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	8.0	25
Brandeis University					Assay Description Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).				Chem Biol 17: 1084-91 (2010) Article DOI: 10.1016/j.chembiol.2010.07.014 BindingDB Entry DOI: 10.7270/Q2GH9GF5
					More data for this Ligand-Target Pair