BDBM50294504 2-amino-N-(3-fluorobenzyl)-6-(furan-2-yl)pyrimidine-4-carboxamide::CHEMBL550636

SMILES: Nc1nc(cc(n1)-c1ccco1)C(=O)NCc1cccc(F)c1

InChI Key: InChIKey=WPZSHLBDZYXRMN-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50294504   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50294504 (2-amino-N-(3-fluorobenzyl)-6-(furan-2-yl)pyrimidin...) Show SMILES Nc1nc(cc(n1)-c1ccco1)C(=O)NCc1cccc(F)c1 Show InChI InChI=1S/C16H13FN4O2/c17-11-4-1-3-10(7-11)9-19-15(22)13-8-12(20-16(18)21-13)14-5-2-6-23-14/h1-8H,9H2,(H,19,22)(H2,18,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vernalis (R+D) Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]CGS21680 from human adenosine A2A receptor				Bioorg Med Chem Lett 19: 2664-7 (2009) Article DOI: 10.1016/j.bmcl.2009.03.142 BindingDB Entry DOI: 10.7270/Q2RF5V1M
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50294504 (2-amino-N-(3-fluorobenzyl)-6-(furan-2-yl)pyrimidin...) Show SMILES Nc1nc(cc(n1)-c1ccco1)C(=O)NCc1cccc(F)c1 Show InChI InChI=1S/C16H13FN4O2/c17-11-4-1-3-10(7-11)9-19-15(22)13-8-12(20-16(18)21-13)14-5-2-6-23-14/h1-8H,9H2,(H,19,22)(H2,18,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vernalis (R+D) Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]CGS21680 from human adenosine A1 receptor				Bioorg Med Chem Lett 19: 2664-7 (2009) Article DOI: 10.1016/j.bmcl.2009.03.142 BindingDB Entry DOI: 10.7270/Q2RF5V1M
					More data for this Ligand-Target Pair
Adenosine receptor A2b (Homo sapiens (Human))	BDBM50294504 (2-amino-N-(3-fluorobenzyl)-6-(furan-2-yl)pyrimidin...) Show SMILES Nc1nc(cc(n1)-c1ccco1)C(=O)NCc1cccc(F)c1 Show InChI InChI=1S/C16H13FN4O2/c17-11-4-1-3-10(7-11)9-19-15(22)13-8-12(20-16(18)21-13)14-5-2-6-23-14/h1-8H,9H2,(H,19,22)(H2,18,20,21)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	924	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vernalis (R+D) Ltd. Curated by ChEMBL					Assay Description Binding affinity to adenosine A2B receptor				Bioorg Med Chem Lett 19: 2664-7 (2009) Article DOI: 10.1016/j.bmcl.2009.03.142 BindingDB Entry DOI: 10.7270/Q2RF5V1M
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50294504 (2-amino-N-(3-fluorobenzyl)-6-(furan-2-yl)pyrimidin...) Show SMILES Nc1nc(cc(n1)-c1ccco1)C(=O)NCc1cccc(F)c1 Show InChI InChI=1S/C16H13FN4O2/c17-11-4-1-3-10(7-11)9-19-15(22)13-8-12(20-16(18)21-13)14-5-2-6-23-14/h1-8H,9H2,(H,19,22)(H2,18,20,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.06E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vernalis (R+D) Ltd. Curated by ChEMBL					Assay Description Binding affinity to adenosine A3 receptor				Bioorg Med Chem Lett 19: 2664-7 (2009) Article DOI: 10.1016/j.bmcl.2009.03.142 BindingDB Entry DOI: 10.7270/Q2RF5V1M
					More data for this Ligand-Target Pair