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SMILES: [#6]-[#8]-c1ccc(-[#6]-n2c(-[#7]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])nc(=O)n(-c3ccco3)c2=O)cc1

InChI Key: InChIKey=OMYSRCLBSSXZDE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50294584   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prokineticin receptor 1


(Homo sapiens (Human))		BDBM50294584
PNG
(1-(2-(5-(furan-2-yl)-1-(4-methoxybenzyl)-4,6-dioxo...)
Show SMILES [#6]-[#8]-c1ccc(-[#6]-n2c(-[#7]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])nc(=O)n(-c3ccco3)c2=O)cc1
Show InChI InChI=1S/C18H21N7O4/c1-28-13-6-4-12(5-7-13)11-24-16(22-9-8-21-15(19)20)23-17(26)25(18(24)27)14-3-2-10-29-14/h2-7,10H,8-9,11H2,1H3,(H4,19,20,21)(H,22,23,26)
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.59E+3n/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Antagonist activity at human PKR1 expressed in HEK293 cells assessed as inhibition of PK1-induced calcium mobilization by FLIPR assay

Bioorg Med Chem Lett 19: 2661-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.157
BindingDB Entry DOI: 10.7270/Q23N23DG
More data for this
Ligand-Target Pair